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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASGRP2
All Species:
27.58
Human Site:
S397
Identified Species:
67.41
UniProt:
Q7LDG7
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7LDG7
NP_001092140.1
609
69248
S397
S
S
P
T
S
P
T
S
C
T
P
P
P
R
P
Chimpanzee
Pan troglodytes
XP_508531
671
75529
S459
S
S
P
T
S
P
T
S
C
T
P
P
P
R
P
Rhesus Macaque
Macaca mulatta
XP_001118242
840
93530
S628
S
S
P
T
S
P
T
S
C
T
P
P
P
R
P
Dog
Lupus familis
XP_854922
606
68799
S397
S
S
P
T
S
P
T
S
C
T
P
P
P
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9QUG9
608
69427
S397
S
S
P
T
S
P
T
S
C
T
P
P
P
R
P
Rat
Rattus norvegicus
P0C643
608
69273
S397
S
S
P
T
S
P
T
S
C
T
P
P
P
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519551
554
63139
R351
T
A
C
S
L
P
P
R
P
P
V
L
E
E
W
Chicken
Gallus gallus
NP_001006401
691
78529
T393
K
S
P
T
S
P
T
T
P
S
K
P
V
V
P
Frog
Xenopus laevis
Q6DCK3
594
68320
S392
S
T
Q
T
H
A
K
S
P
P
S
P
S
P
P
Zebra Danio
Brachydanio rerio
XP_685135
602
68890
K391
K
L
S
T
S
S
S
K
S
Q
S
P
L
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.4
72.3
97.3
N.A.
96.2
96.8
N.A.
77
47.7
64.1
58.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
90.4
72.3
98.3
N.A.
97.8
98
N.A.
81.6
62
78.1
74.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
53.3
33.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
66.6
40
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
60
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
20
0
0
0
0
0
10
10
0
0
10
0
0
0
0
% K
% Leu:
0
10
0
0
10
0
0
0
0
0
0
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
70
0
0
80
10
0
30
20
60
90
60
10
80
% P
% Gln:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
0
0
0
60
0
% R
% Ser:
70
70
10
10
80
10
10
70
10
10
20
0
10
0
0
% S
% Thr:
10
10
0
90
0
0
70
10
0
60
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _